1994-90

Lillie, B. M.; Avery, M. A. The protection of ketones and aldehydes as 4-[(trimethylsilyl)methyl]-1,3-dioxolanes. Tetrahedron Lett. 1994, 35, 969-972.

Kamchonwongpaisan, S.; Chandra-Ngam, G.; Avery, M. A.; Yuthavong, Y. Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting .alpha.-thalassemic erythrocytes in vitro: competition in drug accumulation with uninfected erythrocytes. J. Clin. Invest. 1994, 93, 467-473.

Avery, M. A.; Gao, F.; Chong, W. K. M.; Hendrickson, T. F.; Inman, W. D. et al. Synthesis, conformational analysis, and antimalarial activity of tricyclic analogs of artemisinin. Tetrahedron 1994, 50, 957-972.

Chong, W. K. M.; Chao, W. R.; Yasuda, D. M.; Johansson, J. G.; Avery, M. A. et al. Antihypercholesterolemic steroids and related pharmaceutical compositions and methods of use. In PCT Int. Appl.; (SRI International, USA). Wo, 1993; pp 87 pp.

Avery, M. A.; Gao, F.; Chong, W. K. M.; Mehrotra, S.; Jennings-White, C. The organic and medicinal chemistry of artemisinin and analogs. Trends in Organic Chemistry 1993, 4, 413-468.

Avery, M. A.; Gao, F.; Chong, W. K. M.; Mehrotra, S.; Milhous, W. K. Structure-activity relationships of the antimalarial agent artemisinin. 1. Synthesis and comparative molecular field analysis of C-9 analogs of artemisinin and 10-deoxoartemisinin. J. Med. Chem. 1993, 36, 4264-4275.

Beatty, M. F.; Jennings-White, C.; Avery, M. A. Stereocontrolled synthesis of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid (Adda), the amino acid characteristics of microcystins and nodularin. J. Chem. Soc., Perkin Trans. 1 1992, 1637-1641.

Avery, M. A.; Chong, W. K. M.; Jennings-White, C. Stereoselective total synthesis of (+)-artemisinin, the antimalarial constituent of Artemisia annua L. J. Am. Chem. Soc. 1992, 114, 974-979.

Beatty, M. F.; Jennings-White, C.; Avery, M. A. Stereocontrolled synthesis of (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4E,6E-dienoic acid (ADDA), the characteristic amino acid of microcystins and nodularin. J. Chem. Soc., Chem. Commun. 1991, 351-352.

Avery, M. A.; Chong, W. K. M.; Bupp, J. Preparation of antimalarial analogs of artemisinin. In PCT Int. Appl.; (SRI International, USA). Wo, 1991; pp 173 pp.

Avery, M. A.; Tanabe, M.; Crowe, D. F.; Detre, G.; Peters, R. H. et al. Synthesis and testing of 17a.beta.-hydroxy-7.alpha.-methyl-D-homoestra-4,16-dien-3-one: a highly potent orally active androgen. Steroids 1990, 55, 59-64.

Avery, M. A.; Chong, W. K. M.; Bupp, J. E. Tricyclic analog of artemisinin: synthesis and antimalarial activity of (+)-4,5-secoartemisinin and (-)-5-nor-4,5-secoartemisinin. J. Chem. Soc., Chem. Commun. 1990, 1487-1489.

Avery, M. A.; Chong, W. K. M.; Detre, G. Synthesis of (+)-8a,9-secoartemisinin and related analogs. Tetrahedron Lett. 1990, 31, 1799-1802.

Avery, M. A.; Detre, G.; Yasuda, D.; Chao, W. R.; Tanabe, M. et al. Synthesis and antiinflammatory activity of novel 12.beta.-substituted analogs of betamethasone. J. Med. Chem. 1990, 33, 1852-1858.

Avery, M. A.; Tanabe, M.; Yasuda, D.; Detre, G. Preparation of 12-.beta.-substituted glucocorticoids, and their use as topically active steroidal anti-inflammatory agents. In U.S.; (SRI International, USA). Us, 1990; pp 14 pp.